What is the difference between federal drug charges and state drug charges?

Drug possession, drug trafficking, and drug manufacturing are all serious crimes that can be prosecuted under both state and federal law. In general, the penalties for federal drug convictions are much harsher than state fines and sentences. Federal sentencing guidelines impose longer prison terms on convicted persons. Drug charges can always be prosecuted as federal crimes any time an accused crosses state lines. Additionally, certain quantities of drugs can propel charges into the federal arena. You will also be charged under federal law if you are arrested by a federal law enforcement official.